Xiaobo Zhong
Professor/Pharmaceutical Science

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Identification and Functional Characterization of Alternative Transcripts of LncRNA HNF1A-AS1 and Their Impacts on Cell Growth, Differentiation, Liver Diseases, and in Response to Drug Induction
2024
Ragui Sadek, Grace L. Guo, Timothy M. Schmitt, Jing Jin, Andrew Wassef, Le Tra Giang Nguyen, xiaobo zhong, Theodore Rasmussen
Research Type: Journal Article

The long noncoding RNA HNF1A-AS1 with dual functions in the regulation of cytochrome P450 3A4
2024
Qi Wang, Pei Wang, Wanglai Hu, Yiting Wang, Lirong Zhang, Rick F. Thorne, xiaobo zhong, Shitong Chen, Xiaofei Wang, Shengna Han
Research Type: Journal Article

Special Section on Cytochrome P450 Enzymes in Toxicology and as Drug Targets-Editorial
2024
xiaobo zhong, Yurong Lai
Research Type: Journal Article

Targeting the liver with nucleic acid therapeutics for the treatment of systemic diseases of liver origin.
2024
Anagha Gogate, Prajith Stephen, Sherouk M Tawfik, Milan Shah, Jose E Manautou, Holly Kolmel, Jordyn Belcourt, Jing Jin, Theodore Rasmussen, Alexis Frankel, Raman Bahal, Alicia Zongxun Wang, Matthew Chalon, xiaobo zhong, Aarush Kolli
Research Type: Journal Article

50th anniversary celebration collection: Special section on new and emerging areas and technologies in drug metabolism and disposition, Part I – Editorial.
2023
Yurong Lai, xiaobo zhong, Xinxin Ding
Research Type: Journal Article

A holistic analysis of the intrinsic and delivery-mediated toxicity of siRNA therapeutics.
2023
Jose E Manautou, xiaobo zhong, Xiuling Lu, Sheyda Ranjbar
Research Type: Journal Article

50th anniversary celebration collection: Special section on drug metabolism and precision medicine - Editorial
2023
Yurong Lai, xiaobo zhong
Research Type: Journal Article

50th anniversary celebration collection: Special section on perspective on drug metabolism and precision, Part II – Editorial
2023
Xinxin Ding, xiaobo zhong
Research Type: Journal Article

50th anniversary celebration collection: Special section on xenobiotic receptors - Editorial.
2023
xiaobo zhong, Yurong Lai
Research Type: Journal Article

Epigenetic mechanisms contribute to intraindividual variations of drug metabolism mediated by cytochrome P450 enzymes
2023
Jing Jin, xiaobo zhong
Research Type: Journal Article

ASO drug Qalsody (tofersen) targets amyotrophic lateral sclerosis
2023
xiaobo zhong, Jing Jin
Research Type: Journal Article

50th anniversary celebration collection: Special section on mechanism-based predictive methods in drug discovery and development – Editorial
2023
xiaobo zhong, Yurong Lai
Research Type: Journal Article

Special Section on Drug Metabolism in Liver Injury and Repair - Editorial
2022
xiaobo zhong, Yurong Lai
Research Type: Journal Article

Special section on new era of transporter science: unraveling the functional role of orphan transporters - Editorial.
2022
Xiaobo Zhong, Yurong Lai
Research Type: Journal Article

Effects of overexpression of fibroblast growth factor 15/19 on hepatic drug metabolizing enzymes
2022
Celine Park, Albert Li, Grace L Guo, Jian Shi, Hongbing Wang, Anna SiemiƒÖtkowska, Hao-jie Zhu, Stephanie Piekos, Jie Lu, Liming Chen, Linhao Li, Leonid Kagan, Qian Yang, Bo Kong, xiaobo zhong, Daniel Rizzolo
Research Type: Journal Article

Absorption, Distribution, Metabolism, and Excretion of US Food and Drug Administration–Approved Antisense Oligonucleotide Drugs
2022
Sunna Liu, xiaobo zhong, Sreenidhi Nair, Theodore Rasmussen, Anna Liu, Anagha Gogate, Raman Bahal, Julia M Migliorati, Jose E Manautou
Research Type: Journal Article

Special section on mechanistic and translational research on transporters in toxicology- Editorial
2022
Xiaobo Zhong, Yurong Lai
Research Type: Journal Article

Nephrotoxicity of marketed antisense oligonucleotide drugs
2022
Feryal Alhamadani, Rajvi Parikh, Theodore Rasmussen, Evan M McCabe, SooWan Lee, Xiaobo Zhong, Jose E Manautou, Aniket Wahane, Hangyu Wu, Raman Bahal, Kristy Zhang
Research Type: Journal Article

Nedosiran, a candidate siRNA drug for the treatment of primary hyperoxaluria: design, development, and clinical studies.
2022
Jose E Manaoutou, Jenny Zhao, Anna Liu, Sherouk M Tawfik, Julia M Migliorati, xiaobo zhong, Milan Shah, Raman Bahal, Theodore P Rasmussen
Research Type: Journal Article

Special Section on Bile Acids, Drug Metabolism, and Toxicity—Editorial
2022
Yurong Lai, xiaobo zhong
Research Type: Journal Article