Xiaobo Zhong
Professor/Pharmaceutical Science

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Scholarly Contributions

138 Scholarly Contributions

78
Journal Articles
52
Poster/Presentations
6
Conference Proceedings
2
Other Scholarly Works
ADME features of antisense oligonucleotide and siRNA drugs
2023
xiaobo zhong
Research Type: Poster/Presentation

Challenges of adverse reactions and toxicity for ASO and siRNA drug discovery and development
2023
xiaobo zhong
Research Type: Poster/Presentation

Targeting liver with nucleic acid therapeutics for the treatment of liver-originated systemic diseases
2022
xiaobo zhong
Research Type: Poster/Presentation

Absorption, distribution, metabolism, and excretion of the FDA-approved antisense oligonucleotide drugs
2022
xiaobo zhong
Research Type: Poster/Presentation

Molecular mechanisms of ADME of nucleic acid drugs
2022
xiaobo zhong
Research Type: Poster/Presentation

Roles of lncRNAs HNF1A-AS1 and HNF4A-AS1 in drug metabolism and drug-induced toxicity.
2022
xiaobo zhong
Research Type: Poster/Presentation

Short and long-term alterations of ADME for drug efficacy and toxicity by drug treatment at neonatal and infant ages in preclinical species.
2021
xiaobo zhong
Research Type: Poster/Presentation

An injured liver caused by overdose of acetaminophen has altered expression and activities of P450 enzymes and associated drug efficacy during liver recovery and regeneration.
2021
xiaobo zhong
Research Type: Poster/Presentation

Alterations of cytochrome P450-mediated drug metabolism and therapeutic efficacy during liver recovery and regeneration after acetaminophen-induced liver injury.
2021
xiaobo zhong
Research Type: Poster/Presentation

Acute drug-induced liver injury with medications used in the COVID-19 pandemic.
2020
xiaobo zhong
Research Type: Poster/Presentation

Alterations of drug metabolism and therapeutic efficacy during liver recovery and regeneration after acetaminophen-induced liver injury.
2020
xiaobo zhong
Research Type: Poster/Presentation

Histone 3 lysine 9 methylating enzyme G9a is involved in transcriptional regulation of expression of nuclear receptors and cytochrome P450 genes in HepaRG cells.
2020
xiaobo zhong
Research Type: Poster/Presentation

Impacts on hepatic ontogenic expression of drug-metabolizing enzymes by high-fat diet-induced obesity in mice
2019
Xueyan Shao, Liming Chen, Yifan Bao, Pei Wang, Lirong May Zhang, xiaobo zhong
Research Type: Poster/Presentation

Drug metabolism under drug-induced liver injury
2019
Xiao-bo Zhong
Research Type: Poster/Presentation

Impact on acetaminophen-induced hepatotoxicity by long non-coding RNAs HNF1-AS1 and HNF4-AS1 in HepaRG cells
2019
Jose E Manautou, Liming Chen, Xiao-bo Zhong
Research Type: Poster/Presentation

Alterations of expression and functions of drug metabolizing P450 enzymes in injured liver induced by acetaminophen in mice at different ages
2019
Xiao-bo Zhong, Yifan Bao
Research Type: Poster/Presentation

Phenobarbital increased hepatic toxicity of acetaminophen due to cytochrome P450 induction in young and adult mice
2019
Pei Wang, Yifan Bao, Liming Chen, xiaobo zhong, Xueyan Shao
Research Type: Poster/Presentation

Development of precision medicine based on drug metabolism
2018
xiaobo zhong
Research Type: Poster/Presentation

Short and long-term effects of phenytoin exposure on the liver proteome of neonatal and adult mice using SWATH-MS technology
2018
Xinyue Jing, Jian Shi, Liming Chen, Stephanie C Piekos, Haojie Zhu, xiaobo zhong
Research Type: Poster/Presentation

A transcriptional regulatory network containing nuclear receptors and long non-coding RNAs controls basal and induced expression of cytochrome P450s in liver cells
2018
Yifan Bao, Stephanie C Piekos, Liming Chen, xiaobo zhong
Research Type: Poster/Presentation